Mechanical processing of hydroxyapatite through sintering and multi-objective optimization technique for biomedical application

Abstract Hydroxyapatite (HAp) has been widely applied in the area of tissue engineering, however, its poor mechanical properties limit it load bearing biomedical application. To improve integrity HAp, this study reports synthesis, optimization and significance processing parameters on physic-mechanical HAp. The HAp was produced from biogenic source through at 900 °C. L9 Taguchi orthogonal array employed, considering two namely, particle size (100, 300, 600 $$\mathrm{\mu m}$$ μ m ) compaction (3, 6, 9 KN). raw bones (RB) synthesized were characterized for phase structure functional groups analysis. analysis showed characteristics a typical calcium phosphate material. multiple response revealed that 6 KN are optimal manufacturing high performance Graphical